Howdy folks. So, I'm new around here and I admit this may have been brought up somewhere in the 51-page thread, but I wanted to bounce my personal theory off everyones' collective skulls. First, I admit I'm not a pilot, but I've had an infatuation with flight since I was...hrm...4? 5? Somewhere around there. Every chance to get in a plane I take, and anything involving aircraft I read, watch, or take part in whenever possible.

Anywho...here's my theory based on the (scanty and subject to change minute by minute) evidence and what I have studied. To me, it really sounds like hypoxia based on the time contact was lost and the subsequent actions of the flight crew. The most logical explanation is a slow loss of cabin pressure due to a) mechanical failure, b) design faults with the pressurization systems, or c) human error (Helios flight 322 as an example for how this can happen) that snuck up on the crew and caused everyone on the plane to become anoxic. It would also handily account for the inexplicable behavior of the flight officers in climbing, descending, and turning onto a new heading (or programming one in), turning off the transponder, mubling incoherently into the mic when called by another plane, and any other number of wacked-out things the human brain does when deprived of oxygen.

Also, I was surfing around some forums on AvSim and a lot of the participants there were reporting that the 777 seemed to have problems pressurizing correctly when departing from high-altitude runways. Now, KL is sea level, so not sure if that would cause a similar problem, but it seems like it would have been reported by now if so, so I doubt that's the issue. The likliest cause in my mind is either some sort of maintenance problem or human screw-up, especially considering the vast majority of crashes seem to revolve around the common denominators of human error or equipment failure.

That's my best guess speculation, anyhow. Everyone on that flight was hypoxic 60-90 minutes in, and most likely in irreversible comas when it ran out of gas and coasted into the water at 450 knots 5ish hours later.

Opinions? Rebuttals? Derision? Hit me, I can take it.

**EDIT** Hey, look....there's actually 100 pages in this thread and a few posts that touch on this. I'm observant...