With a car rental out of Whitehorse you can hike the Chilkoot Trail - following the route taken in the Gold Rush (NB a permit is required):

http://www.pc.gc.ca/eng/lhn-nhs/yt/c.../activ1_a.aspx

Personally, I like Stewart BC, but you can use this online guide to plan a circular driving route:

http://www.th.gov.bc.ca/popular-topi...wy37/hwy37.htm

Haines is also very beautiful. You probably need to take the Alaska Marine Highway ferry to reach it:

http://www.dot.state.ak.us/amhs/