iPhone is definitely easier to use out of the box. (Though that may be changing.) Android is much more customizable, which means more options, but can get more confusing.
Because there's just the iPhone with iOS, there's a lot more info regarding it online. With Android, you have fragmentation, so different versions of Android are around. Couple that with different "skins," or overlays, such as HTC's Sense, Samsung's TouchWiz, and Motorola's Blur. This further complicates matters. It also means that what's true for your phone isn't true for mine. So Android may be more popular than iOS, but the iPhone is one of the most popular phones, meaning more resources than other phones.