Thanks UAPremExecflyer, Swiss Tony, and Oxon Flyer.

I will be arriving around 21:30 and leaving for an 8:30 flight, both flights will be in Terminal 5. I saw a pretty good price at the Sheraton Skyline as well and was considering, but saw some mixed reviews. Oxon Flyer, the hotel you're referring to seems like a different hotel, right? You're suggesting the one on Colnbrook Bypass?