If I say I've been to San Francisco over 10 times, and am back again in July, you might guess that I quite like the city!
Some of those visits have been quite short, but even so I've probably spent something around 50-odd days there in total. I haven't, by a very long way, seen everything that I want to.
OP - if any of that tourist experience is useful to you, or you'd like some hotel recommendations that aren't chains and therefore offer much better value, then please feel free to PM me.
A week is no-where near enough, but it'll certainly be sufficient to make you want to go back again.