Wow, so there really ARE women on this site! Nice to meet you, ladies. I've given up on eye makeup on the plane for long-hauls - the eyemask is going to be on for most of it anyway. I love the Ole Henriksen Truth To Go wipes from Sephora - they smell like orange and vanilla. And after I use it on my face, I'll wipe down the arms of the chair so I feel ever so slightly less grimy. I'll do one before I sleep and put on moisturizer, and then another when I wake up, with more moisturizer. And deodorant. And I'll keep lip gloss and mascara in my purse at my feet. I accept that I'll look like crap going through customs, but I'm almost 40 and married, so I guess I'm over it. I'll at least feel (and smell) human.
For clothes, I love to just thrown on leggings, a long top, a wrap sweater, and soft boots that cover my compression socks. There really is a happy medium between business suits and pajamas.