95% of the guests staying at the Andaz were not born, probably not even planned on the day the Regency Mission Bay aka Islandia opened its doors.
The sea lions on the pier are sensational for me as a Western European, but the Grand is the best Hyatt in town. Aviara is not located in San Diego and depending on the traffic an hour away.
If you have to be in downtown San Diego, the Sheraton Suites are a good alternative as well.