I need to make a reservation to LAX. Without the ability to do multi-city, I can't get the lowest fare on AC's main site even though it's available on flights I wanted. And the search by fare functionality is not exactly the brightest. To get the lowest fare, I will need to take the 0700 to YYC and then connect to the 1135 flight to LAX; AC's main site does not return this.
So I am left with one choice if I want to earn miles for my purchase and save $5 - Destina. It prices it out with the multi-city function and they even offer more points than AC's main site.
[Don't worry - haven't bought it yet. Not so sure about buying on Destina.

]
Another stupid thing - the inability to make connections when booking those new domestic fares. So if the nonstop flights are sold out, you can't get those fares even if it's available by connecting.