For the wine.....
Drive this way....You could reverse it
Moth Cascades drive through on WA20 then through Winthrop to Chelan down to Wenatchee/Leavenworth, down to Yakima then thru mt rainier back to Seattle
There are wineries all along the east Washington part.
From around Winthrop, through Chelan, down to Leavenworth you can ind wineries. In Leavenworth there are a few wine stores with tasting rooms.
Just south of Yakima there is an area called rattlesnake Hills.
http://rattlesnakehills.org/
http://www.leavenworth.org/experience/wineries
http://www.lostriverwinery.com/
Also along this area are fruit farms with roadside places to stop.
Just outside of Yakima on US 12 there are a few of these.