Depends a bit on your kids. Myanmar can be difficult for anyone. The infrastructure is not especially well-developed. How do your kids handle adversity? How well do you handle it? The domestic airports are small and crowded.

Myanmar is a very poor country...or at least the people are generally quite poor. How well will your kids deal with that? It could be a very good learning experience.

I agree that pre-arranging guides and transport can certainly make the trip smoother. The people are very nice and friendly. And as with everywhere else they love kids.