My son has successfully bid MSP-AMS a number of times. He tends to get USAir. I don't know the exact savings, but he feels it worth his time and effort.
Bidding is of course free, so all you waste is your time and effort.
There aren't a lot of reported great deals, but one never knows. They can happen.
I don't see the capability of bidding open-jaw, but there is one-way bidding.
Betterbidding has information on how to get many bids in the same 24-hour time period.
Romelle