The card advice others have posted seems good.

For me, I also like to gauge the value of the redemption. You should weigh the costs of using 120-150k miles for flights (plus possible taxes/fuel surcharges) along with possibly (likely?) less desirable routes/timetables against the fact that you could purchase the tickets for $2-3K (with possible spend bonuses on your card for buying airline tickets).

If possible, consider using some extra miles to obtain a business class award, or perhaps adding in extra stops to your trip to maximize value.