I've been doing more research on where to stay, and it seems that it comes down to either Shibuya or Shinjuku. From my impression, it seems Shibuya is more central with closer access to Roppongi. On the other hand, Shinjuku is more of a transportation hub with easier train access to Kyoto and NRT.

As a brief backgrounder, we are from the NYC area, in our early 30s. We aren't really in Japan for shopping, but more for the restaurants, culture, and nightlife. Shopping would maybe consist of some handicrafts and stuff but not brands or designer goods since we have them in NY. In terms of restaurants, we are foodies so we want to try traditional Japanese food for pretty much all meals, but we do want a good value so foodie hole in the walls are a plus. For nightlife, we like bars and maybe lounges every now and then, but not clubs. In NYC, we tend to hang out in the East Village/Soho/Lower East Side and Brooklyn.

We want a convenient and centrally located hotel so we were looking at the following hotels, 1 room for 2 adults.

Shibuya
-Shibuya Excel Tokyu - $231 Excel Twin Non-Smoking
-Shibuya Tokyu Inn - $100 - Single Room, 1 Single Bed
-Dormy Inn - $150 - Double Room

Shinjuku
-Hotel Sunroute - $129 - 1 Double Bed
-Hotel Century Southern Tower - $154 Standard Double

Where should we stay - Shibuya or Shinjuku? Which hotel?