Assuming you mean flying from HNL to JHM in lieu of flying HNL to OGG then driving to Ka'anapali.
I like flying into JHM for the ease of access to Ka'anapali and Kapalua, but the 45 minute drive from OGG to the west side is a nice drive with a good chance to scope out a little bit of Maui if you're going to be spending most of your time in and around Ka'anapali.
Last time we flew from HNL to JHM (this past March) we saw a pod of whales just off the Ka'anapali coast so it was definitely a positive to be flying into JHM.