I would be reluctant to do same-day positioning on B6. Especially in winter. Or summer. Or anytime in between.
They are a fine airline to fly when the sun is shining, but when the stuff hits the fan, no interline agreements and two east coast hubs will kill you.
But otherwise, yes, of course your nuts. Many of us on FT (well at least in the MR forum) would go EWR-IAH-DEN-ORD before starting our trip to TLV!