What happening with me at Pullman Ambassador Seoul was different.
Was forgot handbag at reception and realized it only at the airport, call the hotel, cancelled flight and return to hotel to collect.
My handbag was already stored at concierge safe box, and i can recognize that it was put there only 15' after i leaved hotel.
So, the handbag was returned to owner with full cash, credit card inside.
In your case, i think that it very unusual, posible it not manager falt, but definitely attempt of housekeeping stolen your wife bag.