Query - When you meant issuer it is banks (like Citi, Chase etc) or was it AMEX, MasterCard, Visa etc.
No Issuing banks wants CC customers which don't generate profits. If they see people misusing CCs then they can shut them down. You can search for threads and you will find lots of info on why the people were shut down.
The plan is to have regular spend put on the cards - food, travel, utility bills etc. If the spend is targeted towards a specific category (eg - 2015.8$ per month at CVS) then bells will start ringing sooner rather than later. Of course people have been putting 3/4 VRs per month but they also ensure that they show some other monthly activity on the card.
Each issuing bank has its own way of approving cards. Eg - Chase limits the max credit that it can give to an individual based on the credit score (history, payments etc). This means that if I have reached the limit then Chase will not extend more credit. The only option is to close some cards or reduce limits on some cards to get a new card. This might not be possible always. So you need to look at other issuers.