Wed Night: Arrive HKIA -> ferry to Macau
Thurs: 1 full day in Macau, overnight in Macau
Fri: Spend half day in Macau. Ferry -> HK
Sat-Mon: Spent in Hong Kong
That way, you can spend Wednesday + Thursday night in Macau at lower hotel rates before the weekend hits. Then Fri, Sat, Sun night in Hong Kong.