Flew to Philadelphia for the purpose of trying the famed Philly Cheesesteaks, whoa what a mistake that was, friggin' cheez whiz. The roast pork was great.
They still don't hold a candle to Chicago's Italian beef sandwiches but of course this Chicago based/grown guy might be biased a bit there.

I'd have to say Singapore is my food runs back in the day when one could get cheap fares from ORD. While sure I was able to get a great return on the miles I would earn, my sole focus when going would be to just eat my way through the endless options in Singapore, what a great food town.

For those that went with me to the Seoul Do, a few years ago, there was no doubt that the trip had a certain food focus to it.