I'm not one to hoard points, but I do have one regret. About six years ago, before I'd even heard of FlyerTalk, I blew a bunch of Membership Rewards on a Tumi messenger bag. Really sturdy bag, but still.
In 2011 I used about 14,000 SkyMiles to get a Bodum coffee grinder, and put about 70,000 more toward gift cards, before the redemption price of those skyrocketed. A friend used his SkyMiles on a vacuum cleaner and a mixer.