Check the mattress seams, you can also turn the covers back and put your laptop (turned on) on the sheet. Turn the lights by the bed off for a few minutes, maybe while you're brushing your teeth and washing your face then turn the lights back on and check the sheets. The warmth of your laptop might make them expose themselves. Use the luggage rack, if there isn't one you can put your suitcase on the ironing board.
I've been bitten twice, both were very nice hotels. If you do get bitten do not take your suitcase into the house! Unpack it outside and carry your clothes directly into the washer and treat everything!! Trust me, you don't want them in your house!