Last October my wife and I did PDX-EWR (red-eye)-DEN-IAH-PDX...home in under 24 hours....earned around 6500 PQMs....since none of the layovers were over 4 hours, the entire trip was upgraded to F with one RPU. This started out as a 2nd PDX-LGA trip I booked during the $129 sale about a year ago but a schedule change or two later, I talked them into letting me fly via EWR instead which allowed me the better lounge (w/showers) and what was originally suppose to be an internationally config 757 from EWR-DEN which was sadly swapped to a 757-300 at the last minute

In retrospect, I probably should have picked up a 3rd one of these trips.