I carry a lot of the same stuff as you do and have become a big fan of Thule backpacks. They are specifically - and smartly - designed for laptops and other electronics, with lots of pockets and pouches and often a crush-proof pocket for phone/glasses. They come in a variety of models in different shapes and sizes. I now have three -- love them all. All are sturdily construted and look great. I am particularly fond of their sling bag, though it won't hold two laptops let alone clothes. The Apple Store has carried Thule in the past, though I didn't see any on my last visit. Amazon also carries them, and sometimes at discounts. Generally they range between $100 and $150 for the models you'd probably be most interested in. Check them out. Best,

AC