Well...not really.

I don't think there's much risk that the 'expedited' screening you receive via Pre is going to leave gaping holes in the security screening.

After all, two of the 'benefits' are the ability to keep shoes and light outerwear on. That 'benefit' has already been extended to kids under 12 and adults 75 and older.

I suspect the xray will be staffed with more experienced techs who are capable of spotting the LGA bag without removal, and with so many travellers carrying Ipads/ereaders/netbooks (which generally don't get removed anyway), it's just not that much more of a risk to allow laptops to stay in the bag.

The 'sterile area' is called that for a reason - security isn't so much about who gets past security as it is about what gets past security. Pre might possibly leave gaps in the former; the latter, not so much.