Hello and welcome to FT.

When travelling as couple, I'd prefer any of the pairs of seats at the rear of the 744. The positive is the window, extra space next to the window seat and more privacy with no one next to you. The negatives are that you are last off the plane (no tight connections!), a little more movement than 10 rows further forward), people hanging around in the aisle waiting for toilets or just hanging around in the back of the plane, unsure if catering starts or finishes here - so choice of meals may be an issue, and (if this is still true as it was on the 743) medical stretcher cases will trump passengers for the AB seats.

I'd go for the 2 seats down the back.