Absolutely!

My own I planned using Google Maps and my thumb.

Flew into Joburg, overnight, flight to Pemba Mozambique for diving (and a wonderful pod of wild dolphins was a plus).

Overlanded to Tanzania (using my thumb expected a 6hr journey that became 16hrs) had to bribe immigration at the border, go from bus to pickup truck to boat (had to carry boat due to low tide) and then 7miles on the back of a local guy on a push bike. Got stuck in Tanzania with no cash, Kenyan tourist hooked us up with a hotel for the night and took us to the local airport to fly up to Dar Es Salam for a 3 day safari, robbed by trickster in Dar of hotel for Zanzibar. Got through Safari and onto Zanzibar and dropped at hotel that shut down 6 years prior (thus confirming we got trickstered) checked in next door at an awesome resort, more diving headed downtown for annual musical festival and 5 dollar lobster.

Flew back to Joburg from Dar, decided 8hrs was enough time to check out the Cradle of Humankind, got lost on way back, missed flight, checked into hotel near airport, went to dinner, forgot to pay (signing the check thinking we had given card already) caught next day by waiter who frog marched us over to restaurant (he was accused of stealing the money for bill) paid bill, explained it was honeymoon.. had entire waitstaff of 20 sign local tribal songs and play music for us. Flew home.

I got a bit better since then at planning, but trust me that was an awesome honeymoon!