It all depends on upgrades. 5-6 CPM was fine for me on AS with close to 100% upgrades.

Normally i go for 4CPM or under. 3.5CPM or less i have to book regardless if i really need the miles or not. I'm willing to go higher for long haul international, it can save me from flying the same domestic itin 4 weekends in a row. Nice to knock out close to an entire elite tier in one long weekend.