There are both advantages and disadvantages to being in the back of the plane.

It can be a bit rougher, and it can be a bit more noisy back there, but often it's less crowded.

Depending on how they deliver the food and drinks they may run out of some choices before they get to you, and it's going to take you longer to get off the plane as everybody in front of you has to get off first.

But if it's not crowded you have a better chance of not having a neighbor way back there than you do up front.