A few years ago, I was on a flight from JFK to CDG (on AA). A woman flying with her son and husband wanted to get more leg room (a bulkhead seat), feigned some illness (hoping it would work). Even though she confessed to her deception, paramedics were called. They were going to eject her from the plane, but over an hour after the original departure time, she was let back on the plane (to a round of "boos" from the pax as she passed them on the way to her original seat).
So if this "trivial" incident was not taken lightly, a real illness (hopefully) will be treated in a very serious way.
It looks like the consensus is not to use feigning illness (or even sniffles) to make the Groper uncomfortable.
It's been said that if 100% of pax opted out of the NoS, the lines would get even longer as the TS"O"s have to grope every single pax when the NoS is in operation. This could theoretically place political pressure on Congress to eliminate the NoS, but you'd probably just wind up with NoSes collecting dust and TSA lines extending out the door.
Has anyone ever ever been harassed by pro-TSA pax behind them in line for opting out of the NoS? "Don't opt out! You're going to hold up the line!"