First time poster and not a frequent flyer. I appreciate your patience and hope you can help.

My 18 year old daughter is traveling to Japan this summer for 6 weeks of study-abroad. She has Type 1 diabetes and wears an insulin pump. She will need to bring enough pump supplies plus test strips, meter, insulin, back-up pump, syringes, emergency glucose, snacks, etc. for the entire 6 weeks. This is a lot of stuff and takes up a small carry-on bag entirely. We don't feel comfortabel checking any of it because it is irreplacable in Japan. She also needs her laptop and has a purse. The purse is small and could fit inside the laptop bag.

She is flying on Delta from IND-MSP-SEA-KIX then NRT-DET-IND. It is very difficult to understand the rules for carry-ons. Will she be able to carry on her purse, laptop, medical supplies plus a carry-on with clothing? She was hoping to not check any baggage.

Also,
she has a wheeled duffle for her carry-on that is 20 x 12 x 12. It is this bag http://http://www.ebags.com/product/a-saks/expandable-20-rolling-trolley-duffel/86271?productid=1125191

This is for her clothes. (The one for medical supplies is more like 15x12x8.) Will that duffle work for a carry-on or is it too big? Is she better off just checking it? She is pretty worried about getting there and not having her stuff. Her classes start the very next day.

Also,
In Indianapolis is her only choice to opt-out of the body scanner and get groped? What about NRT? Her pump is ok to go through a regular metal detector but not the body scanner. How exactly does she opt out? Tell the first person she comes to? The one that looks at licenses and tickets?