Only with a LEQ/IOS add on
Perhaps LEQ-EGLM would work as a scheduled service, with a people-mover from EGLM to LHR.
When we headed to LHR from St Ives for our honeymoon, we drove up the day after the wedding, and stayed in a hotel at LHR before flying Air Canada (!!!) to YVR the next morning.
How about LCY - EXT?
I can't think of a more pointless route, perhaps LCY-BHX would be arguable.
EXT is just over 2 hours from Paddington on the train, it's the extra 3 hours add on to Penzance that means