Been there, done that. After putting my time in in Silicon Valley, I went on to have a successful career in a more normal place, having well outlived the company I worked for in the Valley. It does sometimes get tiresome having to beat off the former colleagues with a stick who want me to come work with them, only to have to disappoint them when I tell them that, for that to happen, we'd have to figure out how I could do it while still living in San Diego.