In Guangdong, many people conflate "N" with "L" (very strange to me) so that "Nanjing" becomes "Lanjing" and then there is the "SH/S" conflation that is prominent through much of the south. These are just two examples of many regional issues, but none are all that difficult to decode. You will figure out how to understand them (not their local dialects, but their versions of Mandarin) in short order, and they all understand standard Mandarin (as it's spoken on TV).