its not going to affect the odds of a 72 hour upgrade unless they increase the amount of seats open for U class in advance
Sure it will. It now costs less for an MVP to buy a fare that automatically snatches a seat out of the U bucket that a Gold is waiting for T-72 to clear into.

And those buckets still exist: LAX and West Coast, ORD, IAH and midcons, Mexico, the California-Hawaii routes, LAX-DCA...
That being said: it's not exactly surprising that AS would rather give that F seat to an MVP who's paying $400 for their fare a week before departure, as opposed to a Gold who's paying $150 and bought the G/T fare on sale a couple of months ago. This seems less objectionable than the Tens Of Dollars™ shenanigans the UA forum regulars rant about, where people are supposedly being upsold into F at checkin inexpensively who aren't elites, and trump elites on the waitlist...
This, like the guest upgrade chip chip chip™, is all about monetizing F. Pity AS doesn't seem to be doing things like, oh, adding power or better seats yet. Perhaps we'll see an announcement about that if AS is really serious about this?