It's actually all depends were you live...
With 35,000 I did one London-Marakkesh-Madrid-Paris...overland Bilbao-London.
This would for sure not be cheap, and it was issue with the multi-carrier chart.
My best score ever I think was 160,000 miles, business class HKG-London-Dublin-Brussels-New York (via London)-Lima-LAX-land-Vancouver-HKG....and Cathay even upgraded me to F on HKG-LHR and YVR-HKG....
Last summer for 95,000 miles...Madrid-Caracas-Lima-La Paz-land-north Chile-Santiago-Easter Island-Buenos Aires-Sao Paolo-land-Rio-Madrid in Y...
Ok, these take some homeworks before oyu even think of calling MPC, but they are pretty goo deals!