LX has a nicer hard product.
OS is a draw for soft product and has better catering.
Personally I would choose whichever flight is direct given that JFK is a fairly short flight overall.
If departing from Vienna OS.
From Zurich/GVA LX.
If lounges are a big deal to you LX has nicer and less crowded lounges in ZRH than OS does in VIE.