Did a three day Safari at Sabi Sands (next to Kruger National Park in South Africa) the weekend before last. We did a morning drive and an afternoon drive each day, each about three hours. Saw an enormous variety of wildlife, and was absolutely delighted. Would have happily done a fourth day, though a fifth might have become repetitive. I guess if you're unlucky and don't see much wildlife, you might be getting bored after two days.
To give you an idea of the variety of wildlife at Sabi Sands:
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