They should be able to handle this at the hotel.

In the worst case, have them adjust the address that gets printed at the top of the bill upon check-out to include your wife's name in the "Address 1" (or "Company") line. Then put the address in "Address 2".

So it will look like:If it's a problem that your name is on the folio at all, then you may be out of luck. If they change the name, then you might not get the points to your account.