I started out as an aisle guy, because I used to get a little (ahem) gassy on flights and would have to go to the restroom frequently to relieve the pressure. (tmi? sorry.)

Now that problem seems to have gone away as I have flown more and more.

Window is my preference especially because I can board early and relax knowing that I don't have to get up to let the window and middle seat into their spaces, and I usually don't need to get up on flights of less than 3-4 hours, so I don't get bothered by folks getting up.