I know that Flyertalkers are generally a hard-drinking bunch. But I've always been surprised at how many of us drink in the air. I realized long ago that alcohol is very, very bad on long flights, especially overnight ones. Surviving jet lag is much harder when drinking, AND you have to work upon arrival. If you don't have to work, who cares?
I'll sometimes have a Mimosa pre-flight drink which helps put me to sleep after take-off, but that's it.
Just about every FA will tell you how you should only drink water and they are the only ones who fly as much or more than we do.
-Stimpy who does 200-300K miles per year. YMMV.