Sonoma Airport Hilton Garden Inn
in Santa Rosa, just off the highway, 101. Not romantic, but nice, good service, nice wine list in the little restaurant/bar. indoor pool/hot tub. clean and fairly new. Just what you would expect from a Hilton Garden Inn.
You really need a car in this area anyway, so if you are looking for convenient, this fits the bill.
I take my Mom and niece there every Christmas for an overnight swim stay-cation (I live 4 miles away).
Calistoga (in Napa)
Many choices, for years we took family vacations there, lots of good choices, quaint little town with 2 blocks of "downtown". Sort of spa relaxed type of town, lots to do within 10 miles, again you need a car.