As far as which is least profitable, I would see which route to NRT has the most Low award space in BE available.
Checking low BE dates over the next two months:
PDX - 18 out, 8 back
SEA - 9 out, 11 back
SFO - 31 out, 12 back
LAX - 40 out, 10 back
MSP - 51 out, 26 back
ATL - 47 out 28 back
JFK - 45 out, 42 back
So, it would seem that PDX and SEA are the tightest for award space, which would indicate they are doing better.
The other interesting thing is that award days overall are far less available on the return NRT-USA segment.