Originally Posted by
LTN Phobia
Could I change the FF programme on the booking despite having Upgraviosed?
You should be able to, as you could have bought the MFU ticket for someone else entirely so there's no necessary reason why the FF number for the passenger must be the same as the FF number from which the BA Miles/Avios were taken to do the MFU.
Of course, it may be a fiddly process.