The main advantage is the award space opens up dramatically with the 380s.
If you have to sell 80 Biz seats on every plane, then there are at least 9 award seats left to sell by the last few days.
If you have a lot of award seats available to sell all the time, then you configured the aircraft wrong. (From the airline standpoint, not the 'I wanna upgrade on a cheapo economy fare' standpoint, that is!)