I think you have to decide what you want from a hotel and what class of hotel you are willing to stay in.
Low end as in Wyndham
or high end as in Marriott or other high end brands.

Where will you be traveling for work and what brand of hotels are in the area or does your corporate specify where you will stay and how much you will be reimbursed.
Are you looking for amenities or points/miles in a hotel program and will you be traveling enough to make elite and obtain the perks if any

IHG priority club points never expire others expire after a certain period.
Will you be able to use them before they expire is another question to ask yourself.

I understand Hyatt is good about outbound transfers of points and some programs are not.
You have a lot of hotel thinking to do and I feel the hotel is more important to your well being than an airline unless you are doing frequent longhauls