There's a long discussion thread someplace about it, but it would be hard to search for because the only terms would be common ones like middle seats, etc.

There were two trains of thought.

Some people did the aisle or window way in the back because nobody wants the middle seat in the back.

Others said they had tremendous success by booking a middle seat way in the back, because two people would not want to split up and most people don't want to book an aisle or window where there is already somebody in the middle.

You can keep moving your seat should somebody take the seat next to you, but with planes as full as they have been the odds of keeping an empty seat next to you are not that great.