Thank you for the responses.
Mia, it would primarily be a backup to my Amex Blue Cash card, which I put the vast majority of spending on. So, probably around $15K a year. However, I may put much more of "Everyday" spending items on it if the return on the Visa is better than the 1.5% on the Blue Cash.
Dada, thank you, that is helpful. I typically fly Delta a lot, but really need to start using Southwest more because my last three flights with Delta have been awful. However, based on your post, I am thinking it may be better to be more flexible.