In manual the emergency slide does not deploy when the door is opened. When doors are set to automatic the slide will deploy when the door is opened, such as in an emergency.

I'd be perfectly calm if some drugged up passenger tried to open the door midflight, because I know its not possible. A single human does not have the strength to overcome the differential pressure on the door. Bravery has nothing to do with it, it's knowledge. I have 100% confidence in the laws of physics continuing to work!