We spent 4 days there in Sept 2006. We took the little public boats everywhere - just followed the printed boat schedules. Super fun. We stayed in Bellagio, which is nice but nothing super special.
Villa Carlotta was a beautiful visit. And the city of Como was pleasant - we had a good luncheon there. These are places I definitely fondly remember.
And if you're friends with him, you may as well see George Clooney's place.
In Italy now in fact - near Siena right now, at Rapalano Terme (sp?).
Enjoy!
Michael