I love the nose FC section on a 747, very quiet and private. I love 4K the best. It has a lovely area to the right on which you can prop your feet, lay out your laptop, books, folders...
I also love the cubby that your head goes into when you put it in the bed position.
Some people complain about galley noise in the last row but I've never really heard much.
Much has been written on the subject of best FC 747 seat. Do some searches and you will find many opinions.